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Article

Pluripotent Stem (VSELs) and Progenitor (EnSCs) Cells Exist in Adult Mouse Uterus and Show Cyclic Changes Across Estrus Cycle.

Reproductive sciences (Thousand Oaks, Calif.) - 1 Jan 2021

Singh Pushpa, Bhartiya Deepa

Abstract excerpt

We have earlier reported pluripotent, very small embryonic-like stem cells (VSELs) and slightly bigger endometrial stem cells (EnSCs) in adult mouse uterus and their regulation by gonadotropin and steroid hormones. VSELs can differentiate into cells of all three lineages in vitro; however, they neither expand readily in vitro nor compliment a developing embryo. In the present study, a robust protocol is described...

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PMID: 32710237
DOI: 10.1007/s43032-020-00250-2

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