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Article

An Ophthalmic Rating Scale to Assess Ocular Involvement in Juvenile CLN3 Disease.

American journal of ophthalmology - 1 Dec 2020

Dulz Simon, Atiskova Yevgeniya, Wibbeler Eva, Wildner Jan, Wagenfeld Lars, Schwering Christoph, Nickel Miriam, Bartsch Udo, Spitzer Martin Stephan, Schulz Angela

Abstract excerpt

PURPOSE: Juvenile CLN3 disease, the most prevalent form of Batten disease, is a progressive neurodegenerative disorder resulting from mutations in the CLN3 gene. The objective of this study was to design an ophthalmic rating scale for CLN3 disease in order to quantify disease progression. DESIGN: Retrospective, cross-sectional study. METHODS: Patients underwent ophthalmic evaluations including visual testing,...

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PMID: 32707205
DOI: 10.1016/j.ajo.2020.07.015

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