Article
Whole-genome analyses reveal gene content differences between nontypeable Haemophilus influenzae isolates from chronic obstructive pulmonary disease compared to other clinical phenotypes.
Microbial genomics - 1 Aug 2020
Kc Rajendra, Leong Kelvin W C, Harkness Nicholas M, Lachowicz Julia, Gautam Sanjay S, Cooley Louise A, McEwan Belinda, Petrovski Steve, Karupiah Gunasegaran, O'Toole Ronan F
Abstract excerpt
Nontypeable Haemophilus influenzae (NTHi) colonizes human upper respiratory airways and plays a key role in the course and pathogenesis of acute exacerbations of chronic obstructive pulmonary disease (COPD). Currently, it is not possible to distinguish COPD isolates of NTHi from other clinical isolates of NTHi using conventional genotyping methods. Here, we analysed the core and accessory genome of 568 NTHi...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.