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Article

Conditional and unconditional genome-wide association study reveal complicate genetic architecture of human body weight and impacts of smoking.

Scientific reports - 22 Jul 2020

Xu Ting, Monir Md Mamun, Lou Xiang-Yang, Xu Haiming, Zhu Jun

Abstract excerpt

To reveal the impacts of smoking on genetic architecture of human body weight, we conducted a genome-wide association study on 5,336 subjects in four ethnic populations from MESA (The Multi-Ethnic Study of Atherosclerosis) data. A full genetic model was applied to association mapping for analyzing genetic effects of additive, dominance, epistasis, and their ethnicity-specific effects. Both the unconditional model...

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Identifiers

PMID: 32699216
DOI: 10.1038/s41598-020-68935-x
PMCID: PMC7376032

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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