Article
A taxonomy of seizure dynamotypes.
eLife - 21 Jul 2020
Saggio Maria Luisa, Crisp Dakota, Scott Jared M, Karoly Philippa, Kuhlmann Levin, Nakatani Mitsuyoshi, Murai Tomohiko, Dümpelmann Matthias, Schulze-Bonhage Andreas, Ikeda Akio, Cook Mark, Gliske Stephen V, Lin Jack, Bernard Christophe, Jirsa Viktor, Stacey William C
Abstract excerpt
Seizures are a disruption of normal brain activity present across a vast range of species and conditions. We introduce an organizing principle that leads to the first objective Taxonomy of Seizure Dynamics (TSD) based on bifurcation theory. The 'dynamotype' of a seizure is the dynamic composition that defines its observable characteristics, including how it starts, evolves and ends. Analyzing over 2000...
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