Article
Radiogenomics for predicting p53 status, PD-L1 expression, and prognosis with machine learning in pancreatic cancer.
British journal of cancer - 1 Oct 2020
Iwatate Yosuke, Hoshino Isamu, Yokota Hajime, Ishige Fumitaka, Itami Makiko, Mori Yasukuni, Chiba Satoshi, Arimitsu Hidehito, Yanagibashi Hiroo, Nagase Hiroki, Takayama Wataru
Abstract excerpt
BACKGROUND: Radiogenomics is an emerging field that integrates "Radiomics" and "Genomics". In the current study, we aimed to predict the genetic information of pancreatic tumours in a simple, inexpensive, and non-invasive manner, using cancer imaging analysis and radiogenomics. We focused on p53 mutations, which are highly implicated in pancreatic ductal adenocarcinoma (PDAC), and PD-L1, a biomarker for immune...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
