Article
Imaging phenotype using 18F-fluorodeoxyglucose positron emission tomography-based radiomics and genetic alterations of pancreatic ductal adenocarcinoma.
European journal of nuclear medicine and molecular imaging - 1 Aug 2020
Lim Chae Hong, Cho Young Seok, Choi Joon Young, Lee Kyung-Han, Lee Jong Kyun, Min Ji Hye, Hyun Seung Hyup
Abstract excerpt
PURPOSE: This study aimed to determine if major gene mutations including in KRAS, SMAD4, TP53, and CDKN2A were related to imaging phenotype using 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)-based radiomics in patients with pancreatic ductal adenocarcinoma (PDAC). METHODS: Data on 48 PDAC patients with pretreatment FDG PET/CT who underwent genomic analysis of their tumor tissue were...
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