Article
Association between the Genetic Variants of Glutathione Peroxidase 4 and Severity of Endometriosis.
International journal of environmental research and public health - 15 Jul 2020
Huang Yun-Yao, Wu Cheng-Hsuan, Liu Chung-Hsien, Yang Shun-Fa, Wang Po-Hui, Lin Long-Yao, Lee Tsung-Hsien, Lee Maw-Sheng
Abstract excerpt
It has been reported that oxidative and nitrative stress might be the pathogenesis of endometriosis. This prospective case-control study attempted to check the connection between single nucleotide polymorphism (SNP) of three antioxidant enzymes (glutathione peroxidase 4 (GPX4), thioredoxin 2 (TXN2), thioredoxin reductase 1 (TXNRD1)) and endometriosis. We recruited 90 patients with histology-approved endometriosis...
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