Article
The relationship between JAK2(V617F) mutation and dermatomyositis-a case report and literature review.
Clinical rheumatology - 1 Mar 2021
Xu Qin, Jin Xuexiao, Jiang Yu, Dang Xin, Han Yongmei
Abstract excerpt
The JAK family (JAK1, JAK2, JAK3, and TYK2) have recently emerged as a potential therapeutic management in controlling severe and refractory dermatomyositis. Meanwhile, the progress in the discovery of JAK blockers is significant, with an increasing number of selective JAK inhibitors reported and some are in or prepare for clinical trials. However, the importance of each JAK in dermatomyositis is unclear, which...
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