Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Irinotecan-Still an Important Player in Cancer Chemotherapy: A Comprehensive Overview.

International journal of molecular sciences - 12 Jul 2020

Kciuk Mateusz, Marciniak Beata, Kontek Renata

Abstract excerpt

Irinotecan has been used in the treatment of various malignancies for many years. Still, the knowledge regarding this drug is expanding. The pharmacogenetics of the drug is the crucial component of response to irinotecan. Furthermore, new formulations of the drug are introduced in order to better deliver the drug and avoid potentially life-threatening side effects. Here, we give a comprehensive overview on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Combined Chemotherapy Protocols
Share to DNA, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Synergism

Share to Irinotecan

Share to Molecular Structure

Share to Nucleic Acid Conformation

Share to Prodrugs

Share to Topoisomerase I Inhibitors

Source

Open in PubMed Open full text

Identifiers

PMID: 32664667
DOI: 10.3390/ijms21144919
PMCID: PMC7404108

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Irinotecan-Still an Important Player in Cancer Chemotherapy: A Comprehensive Overview.PMID 32664667Read ↗

Irinotecan, a key chemotherapeutic drug for metastatic colorectal cancer.Semantic proximity Read ↗

Individualization of Irinotecan Treatment: A Review of Pharmacokinetics, Pharmacodynamics, and Pharmacogenetics.Semantic proximity Read ↗

Pharmacogenetics of Irinotecan Disposition and Toxicity: A ReviewSemantic proximity Read ↗

Pharmacogenetics of IrinotecanSemantic proximity Read ↗

Pharmacogenetics of irinotecan metabolism and transport: an update.Semantic proximity Read ↗

Highlights from the latest articles in pharmacogenomics of irinotecan/cisplatin toxicity.Semantic proximity Read ↗

Leveraging Synergy: The Therapeutic Potential of SN-38 and Immunotherapy in Breast and Prostate Cancer TreatmentSemantic proximity Read ↗

RubitecanSemantic proximity Read ↗

Pharmacokinetic and Pharmacogenetic Markers of Irinotecan Toxicity.Semantic proximity Read ↗

Role of Small Molecule Targeted Compounds in Cancer: Progress, Opportunities, and ChallengesSemantic proximity Read ↗

Cellular irinotecan resistance in colorectal cancer and overcoming irinotecan refractoriness through various combination trials including DNA methyltransferase inhibitors: a reviewSemantic proximity Read ↗

Insights, challenges, and future directions in irinogenetics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.