Article
PRPS-Associated Disorders and the Drosophila Model of Arts Syndrome.
International journal of molecular sciences - 8 Jul 2020
Delos Santos Keemo, Kwon Eunjeong, Moon Nam-Sung
Abstract excerpt
While a plethora of genetic techniques have been developed over the past century, modifying specific sequences of the fruit fly genome has been a difficult, if not impossible task. clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9 truly redefined molecular genetics and provided new tools to model human diseases in Drosophila melanogaster. This is particularly true for genes whose protein...
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