Isothermal nucleic acid amplification techniques for detection and identification of pathogenic fungi: A review

Abstract excerpt

BACKGROUND: Fungal infections have increased during the last years due to the AIDS epidemic and immunosuppressive therapies. The available diagnostic methods, such as culture, histopathology and serology, have several drawbacks regarding sensitivity, specificity and time-consuming, while molecular methods are still expensive and dependent on many devices. In order to overcome these challenges, isothermal nucleic...