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Effect of Genetic Polymorphism on the Response to PDE5 Inhibitors in Patients With Erectile Dysfunction: A Systematic Review and a Critical Appraisal.

Sexual medicine reviews - 1 Oct 2020

Mostafa Taymour, Hassan Ashraf, Alghobary Moheiddin F, Abdelrahman Sherine H

Abstract excerpt

INTRODUCTION: Several treatment strategies are nowadays available for erectile dysfunction (ED) patients. Currently, oral phosphodiesterase type 5 inhibitors (PDE5Is) are the first-line therapy for ED. However, they are effective in all treated cases with variable non-responsiveness. Many factors have been listed for this behavior, but the possibility of gene polymorphisms as an underlying cause has not been...

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PMID: 32636154
DOI: 10.1016/j.sxmr.2020.05.005

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