Article
Targeting DNA Damage Repair Pathways in Pancreatic Adenocarcinoma.
Current treatment options in oncology - 29 Jun 2020
Das Satya, Cardin Dana
Abstract excerpt
OPINION STATEMENT: Metastatic (and locally advanced) pancreatic adenocarcinoma (mPDA) represents a major challenge for the oncology community given the rising mortality burden from the disease and the preponderance of patients diagnosed with unresectable disease. Although systemic therapies have become more potent with the development of fluorouracil, irinotecan, and oxaliplatin (FOLFIRINOX) and gemcitabine plus...
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