Role of prothrombin 19911 A>G polymorphism, blood group and male gender in patients with venous thromboembolism: Results of a German cohort study.

doi:10.1007/s11239-020-02169-6

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Article

Role of prothrombin 19911 A>G polymorphism, blood group and male gender in patients with venous thromboembolism: Results of a German cohort study.

Journal of thrombosis and thrombolysis - 1 Feb 2021

Limperger Verena, Kenet Gili, Kiesau Bettina, Köther Max, Schmeiser Malin, Langer Florian, Juhl David, Shneyder Maria, Franke Andre, Klostermeier Ulrich K, Mesters Rolf, Rühle Frank, Stoll Monika, Steppat Dagmar, Kowalski Dorothee, Rocke Angela, Kuta Piotr, Bajorat Tido, Torge Antje, Neuner Bruno, Junker Ralf, Nowak-Göttl Ulrike

Abstract excerpt

The role of the A>G polymorphism at position 19911 in the prothrombin gene (factor [F] 2 at rs3136516) as a risk factor for venous thromboembolism [VTE] is still unclear. To evaluate the presence of the F2 polymorphism in VTE patients compared to healthy blood donors and to adjust the results for common inherited thrombophilias [IT], age at onset and blood group [BG], and to calculate the risk of VTE recurrence....

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PMID: 32594420
DOI: 10.1007/s11239-020-02169-6
PMCID: PMC7886710

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