Article
Molecular identification of Cryptococcus gattii from cerebrospinal fluid using single-cell sequencing: A case study.
The Journal of infection - 1 Oct 2020
Chen Min, Hong Nan, Hu Shan, Wang Peng, Guan HongZhi, Xiao Meng, Zhu Xinlin, Al-Hatmi Abdullah M S, Zhou Zhe, Gao Lei, Boekhout Teun, Xu Jianping, Xu Yingchun, Liao Wanqing, Yang Ying
Abstract excerpt
A 31-year-old man presented with cryptococcal meningitis (CM) without typical clinical characteristics, but with abnormal walking, difficult leg lifting and frequent falling. He was admitted to Peking Union Medical College Hospital. After multiple tests failed to identify the pathogen, single-cell sequencing (scS) was used to test the cerebrospinal fluid (CSF). Comparing the sequence obtained from single-cell...
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