Article
Relation between sex hormones and leucocyte telomere length in men with idiopathic pulmonary fibrosis.
Respirology (Carlton, Vic.) - 1 Dec 2020
Fang Chuling, Huang Hui, Zhang Qian, Wang Na, Jing Xiaoyan, Guo Jian, Ferianc Martin, Xu Zuojun
Abstract excerpt
BACKGROUND AND OBJECTIVE: IPF is an ageing-related lung disorder featuring progressive lung scarring. IPF patients are frequently identified with short telomeres but coding mutations in telomerase can only explain a minority of cases. Sex hormones regulate telomerase activity in vitro and levels of sex hormones are related to LTL. The objective of this study was to explore whether sex hormones were associated...
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