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Gene Mutation in Neonatal Jaundice - Mutations in UGT1A1 and OATP2 Genes.

Indian journal of pediatrics - 1 Jul 2016

Min Jiang, Jie Luo, Caiyun Yang, Ying Lin, Xuefang Yang

Abstract excerpt

This study evaluated the correlation of UGT1A1, OATP2 gene mutations and hyperbilirubinemia in newborns in Northern China. Gene mutations were analyzed at the 211 locus of UGT1A1 (Gly71Arg) and 388 locus of OATP2 (Asn130Asp). The 226 enrolled infants were divided into high, moderate, and low risk subgroups according to American Academy of Pediatrics guideline. Blood samples of the enrolled infants were collected...

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PMID: 26960716
DOI: 10.1007/s12098-016-2064-8

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