Article
Newborn screening alone insufficient to improve pulmonary outcomes for cystic fibrosis.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society - 1 May 2021
Barreda Christina B, Farrell Philip M, Laxova Anita, Eickhoff Jens C, Braun Andrew T, Coller Ryan J, Rock Michael J
Abstract excerpt
BACKGROUND: The Wisconsin Cystic Fibrosis Neonatal Screening Project was a randomized clinical trial (RCT) revealing that children receiving an early diagnosis of CF via newborn screening (NBS) had improved nutritional outcomes but similar lung disease severity compared to those who presented clinically. Because the evaluations of these subjects by protocol ended in 2012, our objective was to assess long-term...
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