Article
RNA sequencing of plasma exosomes revealed novel functional long noncoding RNAs in hepatocellular carcinoma.
Cancer science - 1 Sept 2020
Huang Xuejing, Sun Liyuan, Wen Sha, Deng Deli, Wan Fengjie, He Xiao, Tian Li, Liang Lifang, Wei Chunmeng, Gao Kaiping, Fu Qiang, Li Yasi, Jiang Jianning, Zhai Rihong, He Min
Abstract excerpt
Exosomal long noncoding RNA (lncRNA) has been found to be associated with the development of cancers. However, the expression characteristics and the biological roles of exosomal lncRNAs in hepatocellular carcinoma (HCC) remain unknown. Here, by RNA sequencing, we found 9440 mRNAs and 8572 lncRNAs were differentially expressed (DE-) in plasma exosomes between HCC patients and healthy controls. Exosomal DE-lncRNAs...
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