Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High Expression of NEK2 and PIM1, but Not PIM3, Is Linked to an Aggressive Phenotype of Bronchopulmonary Neuroendocrine Neoplasms.

Endocrine pathology - 1 Sept 2020

Motylewska Ewelina, Braun Marcin, Stępień Henryk

Abstract excerpt

Dysregulations of the NEK2 and PIM1-3 kinase signaling axes have been implicated in the pathogenesis of several cancers, including those with a neuroendocrine phenotype. However, their impact on bronchopulmonary neuroendocrine neoplasms (BP-NENs) has not been investigated. The aim of this pilot study was to determine mRNA and protein levels of NEK2, PIM1, and PIM3 in a group of 49 patients with BP-NENs: 11...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Neuroendocrine
Share to Disease Progression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasm Invasiveness

Share to Neuroendocrine Tumors

Share to NIMA-Related Kinases

Share to Pilot Projects

Share to Protein Serine-Threonine Kinases

Share to Proto-Oncogene Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 32504181
DOI: 10.1007/s12022-020-09629-y
PMCID: PMC7395916

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High Expression of NEK2 and PIM1, but Not PIM3, Is Linked to an Aggressive Phenotype of Bronchopulmonary Neuroendocrine Neoplasms.PMID 32504181Read ↗

Proteogenomic Characterization of High-Grade Lung Neuroendocrine Carcinoma Deciphers Molecular Diversity and Potential Biomarkers of Different Histological Subtypes in Chinese PopulationSemantic proximity Read ↗

Phosphatidylinositol-3-kinase α catalytic subunit gene somatic mutations in bronchopulmonary neuroendocrine tumours.Semantic proximity Read ↗

New Insights into the Molecular Characteristics of Pulmonary Carcinoids and Large Cell Neuroendocrine Carcinomas, and the Impact on Their Clinical ManagementSemantic proximity Read ↗

Molecular profiling of neuroendocrine malignancies to identify prognostic and therapeutic markers: a Fox Chase Cancer Center Pilot StudySemantic proximity Read ↗

Molecular Subtypes of Extra-pulmonary Neuroendocrine Carcinomas Identified by the Expression of Neuroendocrine Lineage-Specific Transcription FactorsSemantic proximity Read ↗

Identification of MicroRNAs Differentially Expressed in Lung Carcinoid Subtypes and ProgressionSemantic proximity Read ↗

Immunotherapy and potential predictive biomarkers in the treatment of neuroendocrine neoplasia.Semantic proximity Read ↗

A comparative study of neuroendocrine heterogeneity in SCLC and NBLSemantic proximity Read ↗

Genomic Profiling and Clinicopathological Characteristics of Neuroendocrine Tumors of the Lung in East Asian Patients.Semantic proximity Read ↗

Analysis of the effect of NEKs on the prognosis of patients with Non-small-cell lung carcinoma based on bioinformaticsSemantic proximity Read ↗

Molecular Profiling and Survival of Completely Resected Primary Pulmonary Neuroendocrine Carcinoma.Semantic proximity Read ↗

Analysis of the effect of NEKs on the prognosis of patients with non-small-cell lung carcinoma based on bioinformatics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.