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Article

Association of CD8 T cell apoptosis and EGFR mutation in non-small lung cancer patients.

Thoracic cancer - 1 Aug 2020

Zhao Chao, Su Chunxia, Li Xuefei, Zhou Caicun

Abstract excerpt

BACKGROUND: The abundance of tumor infiltrating CD8 T cells is an important parameter for antitumor effect of PD-1/PD-L1 immune checkpoint inhibitors, which is less in epidermal growth factor receptor (EGFR) mutation than wild-type non-small cell lung cancer (NSCLC). The mechanism still requires further study. METHODS: In total 190 surgical lung adenocarcinoma samples were included. EGFR mutation was detected...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32500560
DOI: 10.1111/1759-7714.13504
PMCID: PMC7396381

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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