The sensitivity of DPD scintigraphy to detect transthyretin cardiac amyloidosis in V30M mutation depends on the phenotypic expression of the disease.

doi:10.1080/13506129.2020.1744553

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Article

The sensitivity of DPD scintigraphy to detect transthyretin cardiac amyloidosis in V30M mutation depends on the phenotypic expression of the disease.

Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis - 1 Sept 2020

Azevedo Coutinho Maria C, Cortez-Dias Nuno, Cantinho Guilhermina, Gonçalves Susana, Menezes Miguel Nobre, Guimarães Tatiana, Lima da Silva Gustavo, Francisco Ana Rita, Agostinho João, Santos Laura, Conceição Isabel, Pinto Fausto J

Abstract excerpt

Background: There is a growing need for a non-invasive test to detect cardiac involvement in patients with transthyretin-related hereditary amyloidosis (ATTR) caused by V30M mutation. 99mTc-3,3-diphosphono-1,2-propanodicarboxylic acid (DPD) scintigraphy is a promising method, but its accuracy in this particular mutation remains unknown.Methods: A cohort of 179 patients: 92 with early-onset disease (EoD, symptoms...

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PMID: 32482106
DOI: 10.1080/13506129.2020.1744553

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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