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Article

ARTP mutation and adaptive laboratory evolution improve probiotic performance of Bacillus coagulans.

Applied microbiology and biotechnology - 1 Jul 2020

Liu KaiYue, Fang Hua, Cui FengJie, Nyabako Belinda Amanda, Tao TingLei, Zan XinYi, Chen Huayou, Sun WenJing

Abstract excerpt

Bacillus coagulans is a thermophilic, facultative anaerobic, spore-forming Gram-positive bacterium, which is used as a probiotic in animal feed and human dietary supplements. In the present study, a bile-resistant thermophilic B. coagulans WT-03 strain was isolated and genetically identified. Atmospheric pressure room temperature plasma (ARTP)-induced mutation combined with adaptive laboratory evolution (ALE) was...

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PMID: 32474797
DOI: 10.1007/s00253-020-10703-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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