Pseudomonas aeruginosa Isolates From a Cohort of Mexican Children With Cystic Fibrosis Show Adaptation to a Chronic Phenotype.

doi:10.1097/INF.0000000000002714

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Pseudomonas aeruginosa Isolates From a Cohort of Mexican Children With Cystic Fibrosis Show Adaptation to a Chronic Phenotype.

The Pediatric infectious disease journal - 1 Oct 2020

Rosales-Reyes Roberto, Rodríguez-Alvarado Marian, Lezana-Fernández José Luis, Sánchez-Lozano Joselin Yleana, Gayosso-Vázquez Catalina, Jarillo-Quijada Ma Dolores, Toledano-Tableros José Eduardo, Arredondo-Mercado Martha Jimena, Alcántar-Curiel María Dolores, Lincopan Nilton, Vidal Jorge E, Lascurain Ricardo, Valvano Miguel A, Santos-Preciado José Ignacio

Abstract excerpt

BACKGROUND: Long-term persistence of Pseudomonas aeruginosa in the lung of individuals with cystic fibrosis (CF) is associated with progressive selection of diverse genotypes and phenotypes. This bacterial adaptation leads to chronic infection and increased morbidity and mortality. The aim of this study was to establish the prevalence, clonal relatedness, antimicrobial susceptibility and virulence-associated...

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PMID: 32453200
DOI: 10.1097/INF.0000000000002714

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