Article
Lack of association between COL1A1 and COL9A2 single nucleotide polymorphisms and intervertebral disc degeneration.
British journal of neurosurgery - 1 Feb 2021
Hanaei Sara, Abdollahzade Sina, Sadr Maryam, Fattahi Ehsan, Mirbolouk Mohammad Hossein, Khoshnevisan Alireza, Rezaei Nima
Abstract excerpt
BACKGROUND: Collagens are the main components of the extracellular matrix of intervertebral discs. The genetic mutations in collagen genes could potentially play a causal role in pathophysiology of intervertebral disc degeneration (IVDD). In this study, we investigate the association of COL1A1 and COL9A2 single nucleotide polymorphisms (SNPs) with IVDD. MATERIAL AND METHODS: ninety-six Iranian IVDD patients and...
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