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Article

HPV-related methylation-based reclassification and risk stratification of cervical cancer.

Molecular oncology - 1 Sept 2020

Yang Si, Wu Ying, Wang Shuqian, Xu Peng, Deng Yujiao, Wang Meng, Liu Kang, Tian Tian, Zhu Yuyao, Li Na, Zhou Linghui, Dai Zhijun, Kang Huafeng

Abstract excerpt

Human papillomavirus (HPV) is a clear etiology of cervical cancer (CC). However, the associations between HPV infection and DNA methylation have not been thoroughly investigated. Additionally, it remains unknown whether HPV-related methylation signatures can identify subtypes of CC and stratify the prognosis of CC patients. DNA methylation profiles were obtained from The Cancer Genome Atlas to identify...

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PMID: 32408396
DOI: 10.1002/1878-0261.12709
PMCID: PMC7463306

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KRAS
MYC

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