Article
Localized Hypertrophic Neuropathy as a Neoplastic Manifestation of KRAS-Mediated RASopathy.
Journal of neuropathology and experimental neurology - 1 Jun 2020
Vizcaino M Adelita, Belzberg Allan, Ahlawat Shivani, Belakhoua Sarra, Chen Liam, Staedtke Verena, Rodriguez Fausto J
Abstract excerpt
Localized hypertrophic neuropathy is a rare Schwann cell proliferation that usually affects single nerves from the extremities, and it is of unclear etiology in its pure form. RASopathies are a defined group of genetic diseases with overlapping clinical features, usually secondary to germline mutations in genes encoding either components or regulators of the RAS/MAPK pathway. Herein, we report an 11-year-old boy...
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