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Unexpected Short-Tandem-Repeat Patterns in Posttransplant Chimerism Testing: Investigation of 3 Cases with Help from Forensic Science.

Laboratory medicine - 2 Nov 2020

Gvozdjan Kristina, Casey Heather, Mowery Carrie, Kumer Lorie, Fisher Carolyn, Tyler Jennifer, Bayerl Mike G, Malysz Jozef, Naik Seema, Rybka Witold, Ehmann Christopher, Claxton David, Mineishi Shin, Baker Maria, Hong Zheng, Shike Hiroko

Abstract excerpt

Chimerism testing by short tandem repeats (STRs) is used to monitor engraftment after allogeneic hematopoietic stem cell transplantation (HSCT). Generally, STR alleles are stable and transferred from parent to child or from donor to recipient. However, 3 cases did not follow this norm. Additional work-up with help from forensic literature solved these mysteries. In case 1, the patient received HSCT from his son....

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PMID: 32383456
DOI: 10.1093/labmed/lmaa022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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