Article
Whole-Genome Deep Sequencing Reveals Host-Driven in-planta Evolution of Columnea Latent Viroid (CLVd) Quasi-Species Populations.
International journal of molecular sciences - 5 May 2020
Tangkanchanapas Parichate, Haegeman Annelies, Ruttink Tom, Höfte Monica, De Jonghe Kris
Abstract excerpt
Columnea latent viroid (CLVd) is one of the most serious tomato diseases. In general, viroids have high mutation rates. This generates a population of variants (so-called quasi-species) that co-exist in their host and exhibit a huge level of genetic diversity. To study the population of CLVd in individual host plants, we used amplicon sequencing using specific CLVd primers linked with a sample-specific index...
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