Persistent infection and promiscuous recombination of multiple genotypes of an RNA virus within a single host generate extensive diversity.

doi:10.1371/journal.pone.0000917

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Article

Persistent infection and promiscuous recombination of multiple genotypes of an RNA virus within a single host generate extensive diversity.

PloS one - 19 Sept 2007

Weng Ziming, Barthelson Roger, Gowda Siddarame, Hilf Mark E, Dawson William O, Galbraith David W, Xiong Zhongguo

Abstract excerpt

Recombination and reassortment of viral genomes are major processes contributing to the creation of new, emerging viruses. These processes are especially significant in long-term persistent infections where multiple viral genotypes co-replicate in a single host, generating abundant genotypic variants, some of which may possess novel host-colonizing and pathogenicity traits. In some plants, successive vegetative...

Topics

Base Sequence
Biodiversity
DNA Primers
Genotype
RNA Viruses
Recombination, Genetic
Reverse Transcriptase Polymerase Chain Reaction

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Identifiers

PMID: 17878952
DOI: 10.1371/journal.pone.0000917
PMCID: PMC1975466

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