Structure, Function, and Regulation of the Essential Virulence Factor Capsular Polysaccharide of Vibrio vulnificus.

doi:10.3390/ijms21093259

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Article

Structure, Function, and Regulation of the Essential Virulence Factor Capsular Polysaccharide of Vibrio vulnificus.

International journal of molecular sciences - 5 May 2020

Pettis Gregg S, Mukerji Aheli S

Abstract excerpt

Vibrio vulnificus populates coastal waters around the world, where it exists freely or becomes concentrated in filter feeding mollusks. It also causes rapid and life-threatening sepsis and wound infections in humans. Of its many virulence factors, it is the V. vulnificus capsule, composed of capsular polysaccharide (CPS), that plays a critical role in evasion of the host innate immune system by conferring...

Topics

Antigens, Bacterial
Bacterial Capsules
Gene Expression
Gene Expression Regulation, Bacterial
Humans
Operon
Phenotype
Polysaccharides, Bacterial
Structure-Activity Relationship
Vibrio Infections
Vibrio vulnificus
Virulence
Virulence Factors

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Identifiers

PMID: 32380667
DOI: 10.3390/ijms21093259
PMCID: PMC7247339

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