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The Transcriptional Aftermath in Two Independently Formed Hybrids of the Opportunistic Pathogen Candida orthopsilosis.

mSphere - 6 May 2020

Hovhannisyan Hrant, Saus Ester, Ksiezopolska Ewa, Gabaldón Toni

Abstract excerpt

Interspecific hybridization can drive evolutionary adaptation to novel environments. The Saccharomycotina clade of budding yeasts includes many hybrid lineages, and hybridization has been proposed as a source for new pathogenic species. Candida orthopsilosis is an emerging opportunistic pathogen for which most clinical isolates are hybrids, each derived from one of at least four independent crosses between the...

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PMID: 32376704
DOI: 10.1128/mSphere.00282-20
PMCID: PMC7203458

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