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Article

Association between genetic variants in the HIF1A-VEGF pathway and left ventricular regional myocardial deformation in patients with hypertrophic cardiomyopathy.

Pediatric research - 1 Feb 2021

Pieles Guido E, Alkon Jaime, Manlhiot Cedric, Fan Chun-Po Steve, Kinnear Caroline, Benson Leland N, Mital Seema, Friedberg Mark K

Abstract excerpt

BACKGROUND: Information on genetic etiology of pediatric hypertrophic cardiomyopathy (HCM) rarely aids in risk stratification and prediction of disease onset. Little data exist on the association between genetic modifiers and phenotypic expression of myocardial performance, hampering an individual precision medicine approach. METHODS: Single-nucleotide polymorphism genotyping for six previously established...

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Share to Cardiomyopathy, Hypertrophic
Share to Echocardiography

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heart Ventricles

Share to Hypoxia-Inducible Factor 1, alpha Subunit

Share to Myocardium

Share to Neovascularization, Pathologic

Share to Vascular Endothelial Growth Factor A

Share to Ventricular Dysfunction, Left

Source

Identifiers

PMID: 32375165
DOI: 10.1038/s41390-020-0929-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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