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Article

Quantifying technical confounders in microbiome studies

28 Apr 2020

Abstract excerpt

AIMS: Recent technical developments have allowed the study of the human microbiome to accelerate at an unprecedented pace. Methodological differences may have considerable impact on the results obtained. Thus, we investigated how different storage, isolation, and DNA extraction methods can influence the characterization of the intestinal microbiome, compared to the impact of true biological signals such as...

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PMID: 32374853
DOI: 10.1093/cvr/cvaa128

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