Article
Double-blind, randomized controlled trial of therapeutic plasma exchanges vs sham exchanges in moderate-to-severe relapses of multiple sclerosis.
Journal of clinical apheresis - 1 Aug 2020
Brochet Bruno, Deloire Mathilde, Germain Christine, Ouallet Jean-Christophe, Wittkop Linda, Dulau Cécile, Perez Paul, Thevenot Florian, De Sèze Jérome, Zéphir Hélène, Vermersch Patrick, Pittion Sophie, Debouverie Marc, Laplaud David-Axel, Clavelou Pierre, Ruet Aurélie
Abstract excerpt
INTRODUCTION: No randomized controlled clinical trial of therapeutic plasma exchanges (TPE) has yet been performed for moderate-to-severe relapses of multiple sclerosis (MS). OBJECTIVE: To compare TPE to sham-TPE in patients with a recent steroid-resistant moderate-to-severe MS relapse. METHODS: Patients presenting with an MS relapse of less than 2 months without improvement and 15 days after a course of steroids...
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