Article
Digital PCR: A Reliable Tool for Analyzing and Monitoring Hematologic Malignancies.
International journal of molecular sciences - 29 Apr 2020
Coccaro Nicoletta, Tota Giuseppina, Anelli Luisa, Zagaria Antonella, Specchia Giorgina, Albano Francesco
Abstract excerpt
The digital polymerase chain reaction (dPCR) is considered to be the third-generation polymerase chain reaction (PCR), as it yields direct, absolute and precise measures of target sequences. dPCR has proven particularly useful for the accurate detection and quantification of low-abundance nucleic acids, highlighting its advantages in cancer diagnosis and in predicting recurrence and monitoring minimal residual...
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