Article
Abnormalities in sodium current and calcium homoeostasis as drivers of arrhythmogenesis in hypertrophic cardiomyopathy.
Cardiovascular research - 15 Jul 2020
Coppini Raffaele, Santini Lorenzo, Olivotto Iacopo, Ackerman Michael J, Cerbai Elisabetta
Abstract excerpt
Hypertrophic cardiomyopathy (HCM) is a common inherited monogenic disease with a prevalence of 1/500 in the general population, representing an important cause of arrhythmic sudden cardiac death (SCD), heart failure, and atrial fibrillation in the young. HCM is a global condition, diagnosed in >50 countries and in all continents. HCM affects people of both sexes and various ethnic and racial origins, with similar...
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