Article
Genetic basis for virulence differences of various Cryptosporidium parvum carcinogenic isolates.
Scientific reports - 30 Apr 2020
Audebert Christophe, Bonardi Franck, Caboche Ségolène, Guyot Karine, Touzet Hélène, Merlin Sophie, Gantois Nausicaa, Creusy Colette, Meloni Dionigia, Mouray Anthony, Viscogliosi Eric, Certad Gabriela, Benamrouz-Vanneste Sadia, Chabé Magali
Abstract excerpt
Cryptosporidium parvum is known to cause life-threatening diarrhea in immunocompromised hosts and was also reported to be capable of inducing digestive adenocarcinoma in a rodent model. Interestingly, three carcinogenic isolates of C. parvum, called DID, TUM1 and CHR, obtained from fecal samples of naturally infected animals or humans, showed higher virulence than the commercially available C. parvum IOWA isolate...
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