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Article

Haem oxygenases play a pivotal role in placental physiology and pathology

15 Mar 2020

Abstract excerpt

BACKGROUND: Haem oxygenases (HO) catabolise haem, which is the prosthetic group of numerous haemoproteins. Thus, multiple primary cellular pathways and functions rely on haem availability. HO exists in two isoforms, both expressed in the placenta, namely HO-1 and HO-2, the first being inducible. Haem oxygenases, particularly HO-1, have garnered specific interest in the field of physiological and pathological...

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PMID: 32347305
DOI: 10.1093/humupd/dmaa014

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