Article
Associations of CXCL1 gene 5'UTR variations with ovarian cancer.
Journal of ovarian research - 23 Apr 2020
Guo Man, Xu Chao, Chen Yan-Zhe, Sun Qi-Wen, Zhao Xin-Ying, Liu Xin, Yang Yi, Hu Yi-Yan, Li Fei-Feng, Liu Shu-Lin
Abstract excerpt
BACKGROUND: There are about 2.4 hundred thousand new cases and 1.5 hundred thousand deaths of ovarian cancer (OC) annually in the world. Chronic inflammation is a risk factor for OC. C-X-C motif chemokine ligand 1 (CXCL1) defects may facilitate inflammation and transactivate EGFR in ovarian cancer, but the precise haplotypes associated with the potential diseases remained largely unknown. In this work, we...
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