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Article

Clinical MEN-1 Among a Large Cohort of Patients With Acromegaly.

The Journal of clinical endocrinology and metabolism - 1 Jun 2020

Nachtigall Lisa B, Guarda Francisco J, Lines Kate E, Ghajar Alireza, Dichtel Laura, Mumbach Giselle, Zhao Wenxiu, Zhang Xun, Tritos Nicholas A, Swearingen Brooke, Miller Karen K, Thakker Rajesh V

Abstract excerpt

CONTEXT: Clinical multiple endocrine neoplasia type 1 (MEN-1) is diagnosed by the presence of at least 2 MEN-1-associated tumors. Many patients with acromegaly and clinical MEN-1 yield negative testing for MEN1 mutations. While cases of acromegaly and primary hyperparathyroidism (PHP) with negative genetic testing have been reported, its prevalence among patients with acromegaly is undetermined, and the clinical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32311048
DOI: 10.1210/clinem/dgaa142
PMCID: PMC7180000

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