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Article

Teasaponin suppresses Candida albicans filamentation by reducing the level of intracellular cAMP

1 Mar 2020

Abstract excerpt

Background: Candidiasis has long been a threat to human health, but cytotoxicity and resistance always block the usefulness of antifungal agents. The ability to switch between yeast and hypha is one of the most discussed virulence trait attributes of the human pathogenic fungus Candida albicans. The morphological transition provides a novel target for developing antifungal drugs. The aim of the present study was...

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PMID: 32309322
DOI: 10.21037/atm.2020.01.124

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