Article
Cost-effectiveness of sequential urate lowering therapies for the management of gout in Singapore.
Journal of medical economics - 1 Aug 2020
Pruis Sil-Ling, Jeon Yunjoo Karris, Pearce Fiona, Thong Bernard Yu-Hor, Aziz Mohamed Ismail Abdul
Abstract excerpt
Aims: Allopurinol is the most common urate lowering therapy (ULT) used to treat gout but may cause life-threatening severe cutaneous adverse reactions (SCAR) in a small number of patients. Risk of SCAR is increased for patients with the HLA-B*58:01 genotype. When alternative ULT is required, febuxostat or probenecid are recommended. The aim of this study was to conduct a cost-utility analysis of sequential ULT...
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