Article
Identification and application of piwi-interacting RNAs from seminal plasma exosomes in Cynoglossus semilaevis.
BMC genomics - 15 Apr 2020
Zhang Bo, Zhao Na, Jia Lei, Che Jinyuan, He Xiaoxu, Liu Kefeng, Bao Baolong
Abstract excerpt
BACKGROUND: Piwi-interacting RNAs (piRNAs) have been linked to epigenetic and post-transcriptional gene silencing of retrotransposons in germ line cells, particularly in spermatogenesis. Exosomes are important mediators of vesicle transport, and the piRNAs in exosomes might play an important role in cell communication and signal pathway regulation. Moreover, exosomic piRNAs are promising biomarkers for disease...
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