Article
When genetic and surname analyses meet historical sources: The C56R mutation associated with factor XI deficiency as a marker of human migration during the Spanish Reconquista.
Medical hypotheses - 1 Aug 2020
Bauduer F, de la Morena-Barrio M E, Salloum-Asfar S, de la Morena-Barrio B, Padilla J, Miñano A, Vicente V, Carbonell P, Corral J, Esteban J
Abstract excerpt
The C56R mutation associated with factor XI deficiency has been first evidenced in individuals from the French Basque Country. Genetic investigations revealed that this mutation occurred about 5400 years ago as a founder effect in this zone. Other cases were subsequently described in Southwestern Europe. Noticeably a cluster of cases was evidenced in Yecla, a small city from the province of Murcia, in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.