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Article

Circulating microRNA/isomiRs as novel biomarkers of esophageal squamous cell carcinoma

6 Apr 2020

Abstract excerpt

BACKGROUND: MicroRNA (miR)s are promising diagnostic biomarkers of cancer. Recent next generation sequencer (NGS) studies have found that isoforms of micro RNA (isomiR) circulate in the bloodstream similarly to mature micro RNA (miR). We hypothesized that combination of circulating miR and isomiRs detected by NGS are potentially powerful cancer biomarker. The present study aimed to investigate their application...

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PMID: 32251457
DOI: 10.1371/journal.pone.0231116

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