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Article

Repeat expansion scanning of the NOTCH2NLC gene in patients with multiple system atrophy

1 Apr 2020

Abstract excerpt

OBJECTIVE: Trinucleotide GGC repeat expansion in the 5'UTR of the NOTCH2NLC gene has been recognized as the pathogenesis of neuronal intranuclear inclusion disease (NIID). Previous studies have described that some NIID patients showed clinical and pathological similarities with multiple system atrophy (MSA). This study aimed to address the possibility that GGC repeat expansion in NOTCH2NLC might be associated...

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PMID: 32250060
DOI: 10.1002/acn3.51021

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Repeat expansion scanning of the NOTCH2NLC gene in patients with multiple system atrophyPMID 32250060Read ↗

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