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Article

Concepts of Double Hit and Triple Hit Disease in Multiple Myeloma, Entity and Prognostic Significance.

Scientific reports - 6 Apr 2020

Baysal Mehmet, Demirci Ufuk, Umit Elif, Kirkizlar Hakki Onur, Atli Emine Ikbal, Gurkan Hakan, Gulsaran Sedanur Karaman, Bas Volkan, Mail Cisem, Demir Ahmet Muzaffer

Abstract excerpt

Risk assessment in newly diagnosed multiple myeloma patients (NDMM) is the first and the most crucial determinant of treatment. With the utilization of FISH analysis as a part of routine practice, high risk Multiple Myeloma (MM) is defined as having at least one of the mutations related with poor prognosis including; t(4;14) t(14;16), t(14;20), del 17p, p53 mutation, gain 1q and del 1p. M-Smart MM risk...

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Identifiers

PMID: 32249811
DOI: 10.1038/s41598-020-62885-0
PMCID: PMC7136246

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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