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Clinical genetic testing for male factor infertility: current applications and future directions

7 Apr 2014

Abstract excerpt

Spermatogenesis involves the aggregated action of up to 2300 genes, any of which, could, potentially, provide targets for diagnostic tests of male factor infertility. Contrary to the previously proposed common variant hypothesis for common diseases such as male infertility, genome-wide association studies and targeted gene sequencing in cohorts of infertile men have identified only a few gene polymorphisms that...

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PMID: 24711280
DOI: 10.1111/j.2047-2927.2014.00200.x

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